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Methaqualone is a sedative and hypnotic medication. It was sold under the brand names Quaalude and Mandrax among others until commercial production was halted due to widespread abuse, among other things. It is a member of the quinazolinone class.
The sedative–hypnotic activity of methaqualone was first noted in the 1950s. In 1962, methaqualone was patented in the United States by Wallace and Tiernan. Its use peaked in the early 1970s for the treatment of insomnia, and as a sedative and muscle relaxant.
Methaqualone became increasingly popular as a recreational drug and club drug in the late 1960s and 1970s, known variously as “ludes” or “sopers” (also “soaps”) in the United States and “mandrakes” and “mandies” in the United Kingdom, Australia and New Zealand.
The substance was sold both as a free base and as salt (hydrochloride)